Our laboratory is investigating how cellular processes govern proper metabolic function and how abnormal physiology leads to metabolic disease. In particular, we apply experimental and computational methods to identify genetic and epigenetic mechanisms regulating metabolism. We are focusing on understanding how genome-wide chromatin changes, which include chromatin accessibility, nuclear localization and dynamics, and genome organization, lead to physiological dysfunction. Our laboratory utilizes functional genomics, chromatin biology, physiology, and transcriptional regulation in a comprehensive approach to decipher molecular mechanisms in mammalian models of human metabolic disease.
December 19, 2019
Our paper is online! https://onlinelibrary.wiley.com/doi/10.1111/acel.13092
November 23, 2019
Our bivalent marks paper has been accepted for publication in Aging Cell! It's been a great month for lab successes!
November 15, 2019
National Institute of Diabetes and Digestive and Kidney Diseases is funding our first R01 application!
August 29, 2019
We are hiring! We are looking for a lab technician and a Research Scientist to join our team.
Apply here for Research Scientist https://uva.wd1.myworkdayjobs.com/en-US/UVAJobs/job/Charlottesville-VA/Research-Scientist-in-Pharmacology--Bochkis-_R0009997
July 1, 2019
A new graduate student started her summer rotation with us. Welcome Swetha!
June 10, 2019
Four new students have joined the lab this summer. Welcome Divya, Jessie, Madison, and Paxton!
May 19, 2019
Our undergraduate researchers Andrew Price and Anthony DeNovio who have been with us since the start of the lab have graduated. Congratulations and best of luck!
April 30th, 2019
Our preprint is on Biorxiv https://www.biorxiv.org/content/10.1101/623975v1
November 7th, 2018
More press coverage of our article in UVA Health System magazine www.nxtbook.com/nxtbooks/manifest/vimvigor_2018winter-uva/index.php#/38
October 24, 2018
Undergraduate researcher Colton Demetriou has joined our lab. Welcome Colton!
October 5, 2018
Mohan and Anita presented their and Andrew’s work at the Pharmacology Retreat.
July 30, 2018
Postdoctoral associate Mohan Manjegowda has joined our lab. Welcome Mohan!
July 2, 2018
Graduate students Abdullah Abood and Jessica Hatter are joining our lab for a summer rotation. Welcome Abdullah and Jessica!
June 18, 2018
Visiting graduate student Anita Salamon has joined the lab. Welcome Anita!
May 30, 2018
More press coverage.
May 28, 2018
Press release for our article
May 18, 2018
Our undergraduate researcher Marissa Patrick has graduated! Congratulations and good luck!
February 27, 2018
Our paper is online!
January 26, 2018
Our paper “Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver” has been accepted for publication in Aging Cell! Congratulations to co-authors Marissa and Andrew!